官网链接
折扣/货期| 货号：31528-1 mg | 规格：1 mg | 目录价：￥56394 |
| 货号：31528-100 µg | 规格：100 µg | 目录价：￥9180 |
| 货号：31528-20 µg | 规格：20 µg | 目录价：￥3528 |
产品详情
产品名称:
IFN-β (human, recombinant)
别名:
Fibroblast Interferon|IFNB1|Interferon-β
产品描述:
Interferon-β (IFN-β) is a cytokine and type I IFN with roles in antiviral responses and regulation of innate and adaptive immunity.{56197} It is produced mainly by fibroblasts in response to viral pathogens, which are detected by a diverse repertoire of pathogen recognition receptors (PRRs).{56197,56198} IFN-β binds to the IFN-α/β receptor (IFNAR) and induces signal transduction through the canonical JAK/STAT signaling pathway to induce the expression of IFN-stimulated genes (ISGs), which encode proteins that have antiviral, antiproliferative, or immunomodulatory properties, leading to the induction of an antiviral state in infected and neighboring cells and inhibiting viral replication.{56197} IFN-β inhibits the replication of a variety of viral pathogens, including severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, and induces cell cycle arrest at the S phase and apoptosis in Huh7 hepatocellular carcinoma cells in vitro.{56199,56200} Formulations containing IFN-β have been used in the treatment of multiple sclerosis. Cayman's IFN-β (human, recombinant) protein can be used for cell-based assays. This protein consists of 166 amino acids, has a calculated molecular weight of 20 kDa, and a predicted N-terminus of Met22 after signal peptide cleavage.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile 10 mM sodium acetate with 40 mM Arg, 0.12 mg/ml Met, 146 mg/ml sucrose, and 0.1% PF-68, pH 4.5
有效期:
365
纯度:
≥95% estimated by SDS-PAGE
您可能感兴趣的产品
Human SLD5 protein, His tag
货号：GTX69573-pro
Human PSMG3 protein, His tag
货号：GTX68801-pro
Human ARL6 protein, His tag
货号：GTX68797-pro
Human HDHD2 protein, His tag
货号：GTX68796-pro
Human TATDN1 protein, His tag
货号：GTX68792-pro
Human ATG10 protein, His tag
货号：GTX68788-pro
Human DYNLRB1 protein, His tag
货号：GTX68785-pro
Human AMMECR1L protein, His tag
货号：GTX68782-pro
促销活动
相关产品推荐
