货号:9001068 | 规格:25 µg | 目录价:¥7056 |
产品详情
产品名称:
FABP4 (human recombinant) FITC conjugated
别名:
A-FABP|Adipocyte FABP|ALBP|aP2|Fatty Acid Binding Protein 4
产品描述:
Fatty acid binding protein 4 (FABP4) is a member of the intracellular lipid-binding protein (iLBP) family.{11979} It is composed of a β-barrel, which forms the lipid-binding site, and two α-helices that form a lid on the β-barrel.{69229} FABP4 is primarily expressed in adipocytes but has also been found in activated macrophages.{12290,12288} It is involved in lipid transport and metabolism, insulin resistance, and angiogenesis, and its expression is induced by long-chain fatty acids and peroxisome proliferator-activated receptor γ (PPARγ) agonists.{11979,12287,3423,69230,7854} Knockout of Fabp4 prevents the development of atherosclerosis in ApoE-/- mice and increases body weight gain and insulin sensitivity in ob/ob mice.{12888,12287} Serum levels of FABP4 are increased in patients with colorectal cancer, and serum and synovial fluid levels of FABP4 are increased in patients with rheumatoid arthritis.{65347,69230} Cayman's FABP4 (human recombinant) FITC conjugated protein is conjugated to fluorescein isothiocyanate (FITC) and can be used for fluorescence applications.
保存温度:
-80
运输温度:
-80
产品形式:
50 mM sodium phosphate, pH 7.2, with 100 mM sodium chloride and 20% glycerol
有效期:
270
纯度:
≥95% (estimated by SDS-PAGE)
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