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EIDD-2801

品牌：Adipogen

官网链接

说明书

折扣/货期

货号：AG-CR1-3733-M010	规格：10 mg	目录价：￥720
货号：AG-CR1-3733-M050	规格：50 mg	目录价：￥1800

产品详情

产品名称:

EIDD-2801

别名:

beta-D-N4-Hydroxycytidine-5'-isopropyl ester; EIDD 2801; MK-4482; Molnupiravir

产品描述:

EIDD-2801 is an orally bioavailable prodrug of the antiviral nucleoside derivative N4-hydroxycytidine (NHC, EIDD-1931). It is a nucleotide analog inhibitor of RNA-dependent RNA polymerases (RdRps). The compound interferes with the action of viral RNA polymerase. It exerts its antiviral action through introduction of copying errors during viral RNA replication. The active drug incorporates into the genome of RNA viruses, leading to an accumulation of mutations known as viral error catastrophe. This mechanism of inhibition of viral replication is also known as lethal mutagenesis. The broad-spectrum antiviral agent EIDD-2801 inhibits viral RNA replication in various unrelated RNA viruses including influenza, Ebola, Venezuelan equine encephalitis virus (VEEV) and coronaviruses, including SARS-CoV, MERS-CoV and SARS-CoV-2. EIDD-2801 has the potential for COVID-19, seasonal and pandemic influenza treatment. Treatment of SARS-CoV-2 infection with EIDD-2801 completely suppressed virus transmission within 24 hours in ferrets.

保存温度:

-20°C

运输温度:

Ambient

预期分子量:

329.3

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.

产地:

瑞士