Tofacitinib . citrate-抑制剂-ELISA_抗体_蛋白_核苷酸_试剂盒-深圳九游会j9网站首页有限公司

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Tofacitinib . citrate

品牌：Adipogen

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说明书

折扣/货期

货号：AG-CR1-3732-M005	规格：5 mg	目录价：￥600
货号：AG-CR1-3732-M025	规格：25 mg	目录价：￥1320
货号：AG-CR1-3732-M100	规格：100 mg	目录价：￥2520

产品详情

产品名称:

Tofacitinib . citrate

别名:

CP-690550; Xeljanz; Tasocitinib

产品描述:

Potent cell permeable JAK3 inhibitor (IC50 = 1nM). Shows also JAK-1 inhibitory activity. Immunosuppressive and anti-inflammatory agent. Inhibits signaling through heterodimeric receptors associated with JAK3, JAK1, or both of them, with functional selectivity over JAK2-paired receptors. Blocks downstream STAT signaling, resulting in potent inhibition of several cytokines, including interleukins 2, 4, 7, 9, 15 and 21, which are integral to lymphocyte activation, function and proliferation. Investigated for several autoimmune disorders including, rheumatoid arthritis and psoriasis. Potent and selective inhibitor of HIV-1 replication and virus reactivation in vitro. It is investigated against the spread of the SARS-CoV-2 (COVID-19). PRK1 inhibitor.

保存温度:

-20°C

运输温度:

Ambient

预期分子量:

312.4 . 192.1

产品形式:

solid

有效期:

Stable for at least 2 years after receipt when stored at -20°C.

产地:

瑞士