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折扣/货期| 货号：32077-1 mg | 规格：1 mg | 目录价：￥38358 |
| 货号：32077-100 µg | 规格：100 µg | 目录价：￥5904 |
产品详情
产品名称:
Adiponectin (mouse, recombinant)
别名:
30 kDa Adipocyte Complement-Related Protein|Adipocyte Complement-Related 30 kDa Protein|Adipocyte, C1q and Collagen Domain-Containing Protein|Adipose Specific Collagen-Like Factor
产品描述:
Adiponectin is a pleiotropic adipokine and homolog of the complement 1q (C1q) family encoded by Adipoq in mice.{52597,54205} It is composed of an N-terminal signal sequence, a hypervariable region, a collagenous domain, and a C-terminal C1q-like globular domain. It is produced in adipocytes, where the 26.4 kDa monomeric protein is post-translationally modified to induce formation of trimer, hexamer, and high molecular weight (HMW) octadecamers that circulate in serum. These adiponectin multimers have distinct biological activities and do not interconvert once present in the circulation. Plasma levels of adiponectin are decreased in ob/ob mice and mice with diet-induced obesity that have insulin resistance, and exogenous administration of adiponectin improves insulin sensitivity in these mice by increasing β-oxidation in the skeletal muscle and reducing hepatic and musculoskeletal triglyceride content.{52597} Chronic administration of adiponectin reduces hyperglycemia, hyperinsulinemia, and body weight in a mouse model of high-fat diet-induced obesity. Cayman's Adiponectin (mouse, recombinant) protein consists of 241 amino acids, has a calculated molecular weight of 26.4 kDa, and a predicted N-terminus of Glu18 after signal peptide cleavage.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile PBS, pH 7.4
有效期:
365
纯度:
≥95% estimated by SDS-PAGE
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