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折扣/货期| 货号：32076-1 mg | 规格：1 mg | 目录价：￥38502 |
| 货号：32076-100 µg | 规格：100 µg | 目录价：￥5580 |
| 货号：32076-20 µg | 规格：20 µg | 目录价：￥2142 |
产品详情
产品名称:
β-NGF (mouse, recombinant)
别名:
NGFβ|β-Nerve Growth Factor
产品描述:
β-Nerve growth factor (β-NGF) is a neurotrophin that is involved in the regulation of growth, proliferation, and survival of sympathetic and sensory neurons.{53786} Ngf encodes pro-NGF, a 27 kDa protein that is composed of an N-terminal signal peptide and α-, γ-, and β-NGF domains. β-NGF, also known as mature or functional NGF, is produced after degradation of the signaling peptide and proteolytic cleavage.{53789,52615} β-NGF homodimerizes and induces neurotropic signaling through tropomyosin-related kinase A (TrkA) and the p75 neurotrophin receptor (p75NTR).{53787} β-NGF is produced by neurons in the cortex, pituitary gland, hippocampus, basal ganglia, thalamus, spinal cord, and retina, as well as in non-neuronal target cells of sympathetic and sensory neurons such as keratinocytes, vascular smooth muscle cells, exocrine salivary glands, and endocrine tissues.{53787,53788} Exogenous administration of β-NGF improves neurological deficits in murine models of traumatic brain injury (TBI).{53787} Exogenous administration of β-NGF also accelerates the rate of skin excision wound healing in rats. Cayman’s β-NGF (mouse, recombinant) protein can be used for cell-based assay applications. This protein consists of 121 amino acids and has a calculated molecular weight of 13.5 kDa.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile 20 mM NaAc, 150 mM sodium chloride, pH 5.5
有效期:
365
纯度:
≥96% estimated by SDS-PAGE
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