货号:SIH-609-5MG | 规格:5 mg | 目录价:¥1080 |
产品详情
产品名称:
10074-G5
别名:
7-Nitro-N-(2-phenylphenyl)-2,1,3-benzoxadiazol-4-amine
产品描述:
c-Myc inhibitor
保存温度:
-20ºC
运输温度:
Shipped Ambient
预期分子量:
332.3
产地:
加拿大
功能与背景:
10074-G5 binds to and distorts the bHLH-ZIP domain of c-Myc, thereby inhibiting c-Myc/Max heterodimer formation and inhibiting its transcriptional activity (1). 10074-G5 is capable of binding and sequestering the intrinsically disordered amyloid-β (Aβ) peptide in its monomeric, soluble state. Our analysis reveals that this compound interacts with Aβ and inhibits both the primary and secondary nucleation pathways in its aggregation process (2).
纯度:
>98% (TLC); NMR (Conforms)
来源:
Synthetic
CAS号:
413611-93-5
分子式:
C18H12N4O3
溶解度:
May be dissolved in DMSO (40 mg/ml)
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