货号:10774 | 规格:25 µg | 目录价:¥5376 |
产品详情
产品名称:
UTX (human, recombinant)
别名:
KDM6A|Ubiquitously Transcribed Tetratricopeptide Repeat X
产品描述:
Ubiquitously transcribed tetratricopeptide repeat X (UTX) gene codes for the widely-expressed UTX protein. The UTX gene is localized on the X chromosome and is a homolog of the ubiquitously transcribed mouse Y chromosome (UTY) gene. UTX gene expression has been shown to evade X-chromosome inactivation.{19495} The JmjC-containing UTX protein is a member of the hydroxylase family of enzymes, which are α-ketoglutarate-dependent Fe (II) oxygenases.{19494} UTX plays a crucial role in epigenetic regulation of gene expression by catalyzing the demethylation of tri-methylated lysine 27 on histone H3.{19496} UTX works in opposition to the polycomb repressive complex 2 (PRC2) group protein EZH2, playing a role in cancers with abberant H3K27 methylation.
保存温度:
-80
运输温度:
-80
有效期:
180
纯度:
≥55% estimated by SDS-PAGE
上一个:DNA Methyltransferase 3L (human recombinant)
下一个:BRD4 bromodomains 1 and 2 (human, recombinant; aa 49-460)
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