货号:702480 | 规格:384 wells | 目录价:¥7658 |
产品详情
产品名称:
sPLA2 (Type X) Inhibitor Screening Assay Kit
别名:
GXsPLA2|Phosphatidylcholine 2-Acylhydrolase 10|PLA2G10|Secretory Phospholipase A2 (Group 10)|Secretory Phospholipase A2 (Group X)|Secretory Phospholipase A2 (mouse Group X)|Secretory Phospholipase A2 (Type X)|sPLA2-X
产品描述:
Cayman’s sPLA2 (Type X) Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for identifying novel inhibitors of human sPLA2 (Type X), a phospholipase that hydrolyzes PE and PC at the sn-2 position. The assay uses a sulfur-containing analog of 1,2-diheptanoyl-sn-glycero-3-PC (di-C7-PC) as a substrate. Upon hydrolysis by sPLA2 (Type X) at the sn-2 position, free thiols can be detected by the sPLA2 Assay Probe resulting in a product that can be easily quantified using its absorbance at a wavelength of 410 nm. The potent and reversible sPLA2 (Type X) inhibitor, sPLA2 Control Inhibitor, also known as LY315920 or varespladib, is included as a positive control and inhibits the enzyme with an IC50 value of approximately 11 nM.
保存温度:
-80
运输温度:
-80
有效期:
365
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