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SET8 (human recombinant)
品牌:Cayman
货号:10319 规格:100 µg 目录价:¥5614
产品详情
产品名称:
SET8 (human recombinant)
别名:
KMT5a|PR-Set7|SET domain-containing (lysine methyltransferase) 8|SETD8
产品描述:
Methylation of lysine can promote transcriptional activation or repression and is critical in regulating histone function. Lysine residues can be mono-, di-, or tri-methylated.{17798} SET8 selectively mono-methylates histone H4 at lysine 20, an event proven to have an important role in chromatin structure and transcriptional activation.{17452,17451} SET8 is also a novel regulator of p53, mono-methylating lysine 382 of the tumor suppressor.{17453} SET8’s ability to suppress p53 transcriptional activity implies that it may play a significant role in tumorigenesis.
保存温度:
-80
运输温度:
-80
产品形式:
50 mM sodium phosphate, pH 7.2, with 100 mM sodium chloride and 20% glycerol
有效期:
180
纯度:
≥90% estimated by SDS-PAGE
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