货号:310-07-100ug | 规格:100ug | 目录价:¥12757 |
货号:310-07-1mg | 规格:1mg | 目录价:¥51148 |
货号:310-07-20ug | 规格:20ug | 目录价:¥2836 |
货号:310-07-250ug | 规格:250ug | 目录价:¥22322 |
货号:310-07-500ug | 规格:500ug | 目录价:¥33176 |
货号:310-07-50ug | 规格:50ug | 目录价:¥7662 |
货号:310-07-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human sTNF Receptor Type I
别名:
Soluble Tumor Necrosis Factor Type I, TNFRSF1A, TNFAR, TNFR60, p55, CD120a
产品描述:
TNFRI belongs to the TNFR superfamily of transmembrane proteins, and is expressed in most cell types. Binding of either TNF-alpha or TNF-beta to TNFRI initiates a signal transduction pathway that results in the activation of the transduction factor NF-kappaB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis. Soluble TNF Receptor I (sTNFRI) is capable of inhibiting TNF-alpha and TNF-beta activities by acting as a decoy receptor that serves as a sink for the TNF ligands. The human TNFRI gene encodes for a 455 amino acid type I transmembrane protein, which contains a 21 amino acid signal sequence, a 190 amino acid extracellular domain, a 23 amino acid transmembrane domain, and a 221 amino acid cytoplasmic domain. Recombinant Human sTNF Receptor Type I is an 18.3 kDa protein (162 amino acid residues) comprising the cysteine-rich, ligand-binding portion of the extracellular domain of the TNFRI protein.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
18.3 kDa
产品形式:
Bulk
产地:
美国
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