货号:310-06-100ug | 规格:100ug | 目录价:¥11550 |
货号:310-06-1mg | 规格:1mg | 目录价:¥51148 |
货号:310-06-250ug | 规格:250ug | 目录价:¥22322 |
货号:310-06-25ug | 规格:25ug | 目录价:¥2900 |
货号:310-06-500ug | 规格:500ug | 目录价:¥33176 |
货号:310-06-5ug | 规格:5ug | 目录价:¥1163 |
产品详情
产品名称:
Recombinant Human TWEAK
别名:
TNF-related weak inducer of apoptosis, TNFSF12, DR3LG, Apo3 Ligand
产品描述:
TWEAK belongs to the TNF family of ligands, and signals through TWEAKR, also known as TNFRSF12A. TWEAK is expressed in a variety of tissues, including the adult heart, pancreas, skeletal muscle, small intestine, spleen and peripheral blood lymphocytes. TWEAK has the ability to induce NF-kappaB activation and chemokine secretion, and to exert an apoptotic activity in certain cells, such as HT-29 human adenocarcinoma cells when cultured in the presence of IFN-gamma. TWEAK also promotes proliferation and migration of endothelial cells. The human TWEAK gene encodes for a 249 amino acid type II transmembrane protein, which contains a 21 amino acid cytoplasmic domain, a 21 amino acid transmembrane domain, and a 207 amino acid extracellular domain. Recombinant Human TWEAK is a soluble 17.0 kDa polypeptide (154 amino acid residues) comprising the TNF-homologous region of TWEAK, and is generated by proteolytic processing of the full length membrane-anchored TWEAK protein.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
17 kDa
产品形式:
Bulk
产地:
美国
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