官网链接
折扣/货期| 货号：310-08-100ug | 规格：100ug | 目录价：￥2850 |
| 货号：310-08-1mg | 规格：1mg | 目录价：￥18849 |
| 货号：310-08-20ug | 规格：20ug | 目录价：￥1169 |
| 货号：310-08-250ug | 规格：250ug | 目录价：￥8224 |
| 货号：310-08-500ug | 规格：500ug | 目录价：￥12223 |
产品详情
产品名称:
Recombinant Human sRANK Receptor
别名:
TNFRSF11A, ODFR (osteoclast differentiation factor receptor), ODAR (osteoclast differentiation and activation receptor), TRANCE Receptor
产品描述:
RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic cell-membrane protein, which, by interacting with RANKL, augments the ability of dendritic. These dendritic cells then stimulate naive T-cell proliferation, and promote the survival of RANK + T-cells. RANK is also expressed in a variety of tissues, including skeletal muscle, thymus, liver, colon, small intestine, and adrenal gland. The RANK/RANKL interaction is important in the regulation of osteoclastogenesis, and in dendritic cell-mediated T-cell immune responses. Impairments in RANK signaling have been implicated in the induction of expansile osteolysis and Paget's disease of bone (PDB2). Recombinant Human sRANK Receptor is a 19.3 kDa polypeptide containing the TNFR-homologous, cysteine-rich portion of the extracellular domain of RANK receptor (175 amino acid residues).
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
19.3 kDa
产品形式:
Standard
产地:
美国
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