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Recombinant Human Neuroserpin
品牌：PeproTech
货号：130-14-100ug 规格：100ug 目录价：￥12819
货号：130-14-1mg 规格：1mg 目录价：￥51397
货号：130-14-250ug 规格：250ug 目录价：￥22431
货号：130-14-25ug 规格：25ug 目录价：￥2910
货号：130-14-500ug 规格：500ug 目录价：￥33338
货号：130-14-5ug 规格：5ug 目录价：￥1169
产品详情
产品名称:
Recombinant Human Neuroserpin
别名:
Serpin I1, Protease inhibitor 12
产品描述:
Neuroserpin is an inhibitory serpin that is expressed predominantly in the central nervous system. Although the physiological target of neuroserpin is still unclear, cumulative evidence suggests that it plays an important role in controlling proteolytic degradation of extracellular matrix (ECM) during synaptogenesis, and the subsequent development of neuronal plasticity. In the adult brain, neuroserpin is secreted from the growth cones of neurons in areas where synaptic changes are associated with learning and memory (i.e. cerebral cortex, hippocampus, and amygdala.) The neuroprotective role of neuroserpin has been demonstrated in transgenic mice lacking neuroserpin expression. The deficiency of neuroserpin in these mice was associated with motor neuron disease characterized by axonal degradation. In humans, defects in neuroserpin, caused by point mutations in the neuroserpin gene, underlie a hereditary disorder called the familial encephalopathy with neuroserpin inclusion bodies (FENIB). Recombinant Human Neuroserpin is a 44.8 kDa non-glycosylated protein containing 395 amino-acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
44.8 kDa
产品形式:
Bulk
产地:
美国
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