Recombinant Human Heregulinbeta-1-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

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Recombinant Human Heregulinbeta-1

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：100-03-100ug	规格：100ug	目录价：￥5760
货号：100-03-10ug	规格：10ug	目录价：￥1163
货号：100-03-1mg	规格：1mg	目录价：￥25574
货号：100-03-250ug	规格：250ug	目录价：￥11161
货号：100-03-500ug	规格：500ug	目录价：￥16583
货号：100-03-50ug	规格：50ug	目录价：￥2900

产品详情

产品名称:

Recombinant Human Heregulinbeta-1

别名:

Neuregulin1 (NRG1-beta1), Neu differentiation factor (rat), HRG, HRG1-beta1, Breast cancer cell differentiation factor p45, ARIA (Acetylcholine, Receptor Inducing Activity), glial growth factor

产品描述:

Neuregulin/Heregulin is a family of structurally-related polypeptide growth factors derived from alternatively spliced genes (NRG1, NRG2, NRG3 and NRG4). To date, there are over 14 soluble and transmembrane proteins derived from the NRG1 gene. Proteolytic processing of the extracellular domain of the transmembrane NRG1 isoforms releases soluble growth factors. HRG1-beta1 contains an Ig domain and an EGF-like domain; the latter is necessary for direct binding to receptor tyrosine kinases erb3 and erb4. This binding induces erb3 and erb4 heterodimerization with erb2, stimulating intrinsic kinase activity that leads to tyrosine phosphorylation. Although HRG1-beta1's biological effects are still unclear, it has been found to promote motility and invasiveness of breast cancer cells, which may also involve up-regulation of expression and function of the autocrine motility-promoting factor (AMF). Recombinant Human Heregulinbeta-1 (HRG1-B1) is a 7.5 kDa polypeptide consisting of only the EGF domain of heregulinbeta-1 (65 amino acid residues).

宿主来源:

E.coli

推荐稀释度:

请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度

预期分子量:

7.5 kDa

产品形式:

Bulk

产地:

美国

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