官网链接
折扣/货期| 货号：100-00CC-100ug | 规格：100ug | 目录价：￥12757 |
| 货号：100-00CC-1mg | 规格：1mg | 目录价：￥51148 |
| 货号：100-00CC-20ug | 规格：20ug | 目录价：￥2836 |
| 货号：100-00CC-250ug | 规格：250ug | 目录价：￥22322 |
| 货号：100-00CC-500ug | 规格：500ug | 目录价：￥33176 |
| 货号：100-00CC-5ug | 规格：5ug | 目录价：￥1163 |
产品详情
产品名称:
Recombinant Human PDGF-CC
别名:
Platelet-Derived Growth Factor-CC
产品描述:
The platelet-derived growth factor (PDGF) family of heparin-binding growth factors consists of five known members, denoted PDGF-AA, PDGF-BB, PDGF-AB, PDGF-CC and PDGF-DD. The mature and active form of these proteins, an anti-parallel, disulfide-linked dimer of two 12-14 kDa, polypeptide chains, is obtained through proteolytic processing of biologically inactive precursor proteins, which contain an N-terminal CUB domain and a PDGF/VEGF homologous domain. The PDGFs interact with two related protein tyrosine kinase receptors, PDGFR-alpha and PDGFR-beta, and are potent mitogens for a variety of cell types, including smooth muscle cells, connective tissue cells, bone and cartilage cells, and certain tumor cells. They play an important role in a number of biological processes, including hyperplasia, chemotaxis, embryonic neuron development, and respiratory tubules' epithelial cell development. Mature PDGFs are stored in platelet alpha-granules, and are released upon platelet activation. PDGF-AA, -AB, -BB and -CC signal primarily through the PDGFR-alpha receptor, whereas PDGF-DD interacts almost exclusively with the PDGFR-beta receptor. Recombinant Human PDGF-CC is a 25.0 kDa protein consisting of two identical disulfide-linked, 112 amino acid, polypeptide chains.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
25 kDa
产品形式:
Bulk
产地:
美国
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