货号:10005615-100 µg | 规格:100 µg | 目录价:¥4620 |
货号:10005615-25 µg | 规格:25 µg | 目录价:¥1302 |
货号:10005615-50 µg | 规格:50 µg | 目录价:¥2464 |
产品详情
产品名称:
PtdIns-(4,5)-P2 (1,2-dipamitoyl)-d62 (sodium salt)
别名:
DPPI-4,5-P2-d62|Phosphatidylinositol-4,5-diphosphate C16-d62|PI(4,5)P2 (16:0/16:0)-d62|PIP2[4',5'](16:0/16:0)-d62
产品描述:
PtdIns-(4,5)-P2 (1,2-dipalmitoyl)-d62 (sodium salt) contains 62 deuterium atoms at the 2, 2', 3, 3', 4, 4', 5, 5', 6, 6', 7, 7', 8, 8', 9, 9', 10, 10', 11, 11', 12, 12', 13, 13', 14, 14', 15, 15', 16, 16, and 16 positions of each fatty acyl chain. It is intended for use as an internal standard for the quantification of PtdIns-(4,5)-P2 (1,2-dipalmitoyl) (sodium salt) by GC- or LC-mass spectrometry. The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-4,5-P2-(1,2-dipalmitoyl)-d62 is a synthetic analog of natural PtdIns containing deuterated C16:0 fatty acids at the sn-1 and sn-2 positions. This synthetic standard features the same inositol and diacyl glycerol (DAG) stereochemistry as that of the natural compound. The natural compound is the product of phosphatidylinositol 4-phosphate 5-kinase acting on PtdIns-(4)-P1. Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade.
保存温度:
-20
运输温度:
-20
预期分子量:
1099.3
产品形式:
A lyophilized powder
有效期:
1825
纯度:
≥99% deuterated forms (d1-d62)
分子式:
C41H16D62O19P3 • 3Na
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