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折扣/货期| 货号：90510-1 mg | 规格：1 mg | 目录价：￥672 |
| 货号：90510-10 mg | 规格：10 mg | 目录价：￥5194 |
| 货号：90510-5 mg | 规格：5 mg | 目录价：￥2940 |
产品详情
产品名称:
O-11
别名:
11-Oxatetradecanoic Acid|FA 13:0;O
产品描述:
O-11 is an analog of the fully saturated, 14-carbon fatty acid myristic acid, in which the methylene group at position 11 is replaced with oxygen. It is highly effective and selective at killing Trypanosoma brucei, the protozoan parasite responsible for African sleeping sickness, exhibiting an LD50 of less than 1 µM in a cell culture assay.{7752,11965} The toxic effects of O-11 appear to be caused by its ability to inhibit the incorporation of a single myristate into the GPI anchor of the variant surface glycoprotein (VSG), a protein critical for evading the host immune response.{7752} O-11 exhibits essentially no anti-fungal activity when assayed using C. neoformans, but does have a minor inhibitory effect on HIV-1 replication in T-lymphocytes.{2338}
保存温度:
-20
运输温度:
-20
预期分子量:
230.3
产品形式:
A solution in methyl acetate
有效期:
365
纯度:
≥98%
CAS号:
119290-12-9
分子式:
C13H26O3
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