货号:10007763-1 mg | 规格:1 mg | 目录价:¥5446 |
货号:10007763-100 µg | 规格:100 µg | 目录价:¥700 |
货号:10007763-500 µg | 规格:500 µg | 目录价:¥3080 |
产品详情
产品名称:
PtdIns-(3,5)-P2 (1,2-dioctanoyl) (sodium salt)
别名:
DOPI-3,5-P2|Phosphatidylinositol-3,5-bisphosphate C-8|PI(3,5)P2 (8:0/8:0)|PIP2[3',5'](8:0/8:0)
产品描述:
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals.{4096,8344} PtdIns-(3,5)-P2 (1,2-dioctanoyl) is a synthetic analog of natural phosphatidylinositol (PtdIns) featuring C8:0 fatty acids at the sn-1 and sn-2 positions. The compound features the same inositol and diacylglycerol (DAG) stereochemistry as the natural compound. PtdIns are phosphorylated to mono- (PtdIns-P; PIP), di- (PtdIns-P2; PIP2), and triphosphates (PtdIns-P3; PIP3). Hydrolysis of PtdIns-(4,5)-P2 by phosphoinositide (PI)-specific phospholipase C generates inositol triphosphate (IP3) and DAG which are key second messengers in an intricate biochemical signal transduction cascade. PtdIns-(3,4)-P2 is resistant to hydrolysis by phospholipase C.{13721}
保存温度:
-20
运输温度:
-20
预期分子量:
812.5
产品形式:
A lyophilized powder
有效期:
1825
纯度:
≥98%
分子式:
C25H46O19P3 • 3Na
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