货号:AG-40T-0107-C050 | 规格:50 ug | 目录价:¥3840 |
产品详情
产品名称:
NAD Kinase (M. tuberculosis) (rec.) (His)
别名:
Probable Inorganic Polyphosphate/ATP-NAD kinase; Poly(P)/ATP NAD Kinase 1; ppnK1; EC 2.7.1.23
产品描述:
NAD kinase catalyzes the transfer of a phosphate group from ATP to NAD+ to generate NADP+, which in its reduced form acts as an electron donor for biosesynthetic reactions. NADP+ is an essential coenzyme in metabolism and provides reducing power to biosesynthetic processes such as fatty acid biosesynthesis. NAD kinase from Mycobacterium tuberculosis is not ATP-dependent but has a broader substrate specificity than human NAD kinase. It can economically produce NADP+ by using other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus. Was identified as a high-confidence drug target. Catalytic activity: ATP + NAD+ = ADP + NADP+
宿主来源:
E. coli
产品浓度:
0.5mg/ml (Lot specific)
保存温度:
-80°C
运输温度:
DRY ICE
预期分子量:
~33.0kDa
产品形式:
liquid
存储溶液:
Liquid. In 10mM TRIS at pH 8.0, containing 1mM MgCl2, 0.5mM EDTA, 1mM DTT and 1mM PMSF.
有效期:
Stable for at least 6 months after receipt when stored at -80°C.
产地:
瑞士
纯度:
>98% (SDS-PAGE)
生物活性:
~1.2 U/mg protein. (Substrate: NAD (+ ATP))
~3.8 U/mg protein. (Substrate: NAD (+ poly(P))
One unit is defined as the amount of enzyme that synthesizes 1µmol nicotinamide adenine dinucleotide phosphate (NADP) per min.
内毒素水平:
N/A
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