货号:10006984 | 规格:1 ea | 目录价:¥1848 |
产品详情
产品名称:
LPA1 Blocking Peptide
别名:
EDG-2|LPA Receptor 1|LPAR1|Vzg-1
产品描述:
To be used in conjunction with Cayman’s LPA1 polyclonal antibody (Catalog No. 10005280) to block protein-antibody complex formation during immunochemical analysis of LPA1. · LPA1 (also known as EDG-2) is one of four known LPA receptors (LPA1-4).{13001} LPA1-3 are part a family of G protein-coupled receptors that share identity to the sphingosine-1-phosphate receptors (S1P1-5).{11049} LPA1 couples with three types of G proteins, Gi/o, Gq, and G12/13 to induce a range of cellular responses including activation of phospholipase C, multiple kinases, the serum response element, and cell proliferation.{11808,12477} LPA1 mRNA is detected in a wide range of tissues and cells including brain, heart, small intestine, spleen, testis, kidney, HeLa cells, and A549 cells.{11810,12912} Murine and human LPA1 have 364 amino acids with an estimated molecular weight of 41 kDa.{12477} Cayman’s LPA1 polyclonal antibody detects the protein from several species at 43-50 kDa, suggesting heterogeneous LPA1 post-translational modifications in distinct cells.
保存温度:
-20
运输温度:
-20
产品形式:
200 µg lyophilized blocking peptide
有效期:
1095
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