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Human complement C3 (active)

品牌：GeneTex

官网链接

说明书

折扣/货期

货号：GTX30711-pro

规格：250μg

目录价：￥6300

产品详情

产品名称:

Human complement C3 (active)

别名:

complement C3 , AHUS5 , ARMD9 , ASP , C3a , C3b , CPAMD1 , HEL-S-62p

产品描述:

Native, human C3 complement component. Glycoprotein composed of two non-identical disulfide-bonded subunits with M.W. of 115 kDa (alpha) and 75 kDa (beta). Present in normal human serum at 1.25 mg/ml. Classical and alternative activation pathways of complement converge at C3 step. Activation via either pathway can result in assembly of C3-cleaving enzymes (C3 convertases) on target surfaces. Both C3 convertases cleave the C3 alpha-chain at peptide bond 77 resulting in production of C3a (M.W. 9.083kDa) and C3b fragments (M.W. 180kDa). Released C3a peptide is one of the three complement anaphylatoxins. The nascent C3b fragment can form a covalent ester bond with target surface. This covalent attachment of C3b to target acceptors is required for continuation of complement activation. This protein was purified from Human Serum (negative for HBsAg and for antibodies to HIV and HCV).

实验应用:

Functional Assay

克隆号:

偶联:

Unconjugated

产品浓度:

Batch dependent (Please refer to the vial label for the specific concentration.)

表达系统:

Human Serum

保存温度:

Store as concentrated solution. Aliquot and store at -20ºC or below. Avoid freeze-thaw cycles.

运输温度: