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折扣/货期| 货号：100024 | 规格：200 µg | 目录价：￥1848 |
产品详情
产品名称:
Hepsin Blocking Peptide (aa 241-260)
产品描述:
Each vial contains 200 µg of lyophilized peptide consisting of human hepsin amino acids 241-260 (GGYLPFRDPNSEENSNDIAL). This peptide can be used in conjunction with Cayman’s hepsin polyclonal antibody - affinity-purified (aa 2416-260) (Item No. 100022) to block protein-antibody complex formation during analysis for hepsin. Hepsin is a type II membrane-associated protein that has a extracellular proteolytic domain and exhibits low sequence homology to other known proteases.{9602,9603} Recently, hepsin overexpression was observed in prostate, breast, kidney, and ovarian cancers and due to low homology to other known proteases may provide a unique target for pharmacological therapy.{9067,9600,9601,9599,9604} Hepsin is necessary for cell growth in vitro{9606} and may play a role in metastatic expansion by factor VII activation.{9598,9599} The observed molecular mass of hepsin by immunoblotting is 45.3 kDa. Cloning and characterization of murine and rat hepsin indicate 88% overall homology with human hepsin.{9596,9597,9605} Northern blotting reveals high levels of hepsin transcripts in liver.{9603,9604}
保存温度:
-20
运输温度:
-20
产品形式:
200 µg of peptide in 200 µl PBS, pH 7.2, containing 0.02% sodium azide
有效期:
1095
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