货号:601120 | 规格:100 tests | 目录价:¥8352 |
产品详情
产品名称:
CYP2C9 Induction Reporter Assay Kit
产品描述:
Early screening of drug candidate’s potential to induce or inhibit CYP2C9 is a critical step in the drug development process. The CYP2C9 Induction Reporter Assay Kit is a novel method to evalsuate CYP2C9 induction by drug candidates. Cayman's CYP2C9 Induction Reporter Assay Kit consists of a 96-well plate coated with a transfection complex containing a Secreted Alkaline Phosphatase (SEAP) reporter regulated by the human CYP2C9 gene promoter. Cells grown on the CYP2C9 Reporter Reverse Transfection Strip Plate will introduce the reporter gene and express GRα as well as HNF4α. Test compounds that promote binding of the nuclear receptors to the CYP2C9 promoter initiates SEAP expression. SEAP activity is subsequently measured using a luminescence readout. The kit is simple to use and can be easily adapted to high-throughput screening for potential nuclear receptor-mediated CYP2C9 inducers.
保存温度:
-20
运输温度:
-20
有效期:
365
您可能感兴趣的产品
CytoSelect™ LDH Cytotoxicity Assay Kit
货号:CBA-241
CytoSelect™ Cell Viability and Cytotoxicity Assay
货号:CBA-240
Mitochondrial PT Pore Assay Kit
货号:601430
LDH Cytotoxicity Assay Kit
货号:601170-480 wells
CYP2C9 Induction Reporter Assay Kit
货号:601120
CYP2B6 Induction Reporter Assay Kit
货号:600680
CYP1A1/2 Induction Reporter Assay Kit
货号:600670
Multidrug Resistance Assay Kit (Calcein AM)
货号:600370
促销活动