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折扣/货期| 货号：32093-50 µg | 规格：50 µg | 目录价：￥3924 |
| 货号：32093-500 µg | 规格：500 µg | 目录价：￥25488 |
产品详情
产品名称:
CXCL12α (human, recombinant)
别名:
Chemokine (C-X-C motif) Ligand 12|Intercrine Reduced in Hepatomas|Pre-B Cell Growth-stimulating Factor|SDF-1|Stromal Cell-derived Factor 1
产品描述:
Chemokine (C-X-C motif) ligand 12 (CXCL12) is a homeostatic chemokine and member of the CXC chemokine subfamily.{56125} Alternative splicing of CXCL12 produces six isoforms that exhibit isoform-specific tissue distribution.{56124} CXCL12α is ubiquitously expressed and is composed of an N-terminal receptor binding domain, a glycosaminoglycan-binding domain, and a C-terminal domain.{56125,56124} CXCL12α binds to atypical chemokine receptor 3 (ACKR3) and chemokine (C-X-C motif) receptor 4 (CXCR4) to induced β-arrestin and G protein-coupled receptor signaling, respectively.{56125} It enhances hematopoietic progenitor cell survival and chemotaxis.{56122} CXCL12α promotes axonal elongation of primary spinal cord motor neurons and administration of an anti-Cxcl12α antibody delays neuromuscular nerve junction regeneration in a mouse model of α-latrotoxin-induced neuromuscular degeneration.{56123} Cayman's CXCL12α (human, recombinant) protein consists of 84 amino acids and has a calculated molecular weight of 10 kDa.
保存温度:
-80
运输温度:
-80
产品形式:
Lyophilized from sterile PBS, pH 7.4
有效期:
365
纯度:
≥90% estimated by SDS-PAGE
上一个:Erythropoietin (human, recombinant)
下一个:Neuregulin-1 Type I-β2b Extracellular Domain (human, recombinant; aa 20-238)
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