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    CGRP Monoclonal Antibody (Clone 4901)
    
                                                
    
                                                        
    
                                
    品牌：Cayman
    
                            
    
                                                        
                        
    
                    
    
                    
    
                        
    
                                                                                    
    
                                货号：29254
                                规格：100 µl
                                目录价：￥7408
                            
    
                                                                                
    
                    
    
                    
    产品详情
    
                    
    
                                                
    
                            
    产品名称:
    
                            
    CGRP Monoclonal Antibody (Clone 4901)
    
                        
    
                                                                        
    
                            
    别名:
    
                            
    Calcitonin Gene-Related Peptide
    
                        
    
                                                                        
    
                            
    产品描述:
    
                            
     Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide.{41395} It exists in two major forms that share greater than 90% sequence homology, α-CGRP that is produced by alternative RNA splicing of the calcitonin gene CALCI and β-CGRP that is encoded by CALCII in humans. CGRP is primarily expressed in A and Cδ fibers and exhibits perivascular localization but is also expressed in keratinocytes and endothelial progenitor cells.{41395,53682} CGRP binds to a heteromeric complex of calcitonin receptor-like receptor (CRLR) and receptor activity-modifying protein 1 (RAMP1) and has roles in efferent function, nociception, and vasodilation. Levels of CGRP are increased in various pain states, including migraine. It also suppresses TNF-α, increases fibroblast motility and extracellular matrix synthesis, and induces Schwann cell proliferation to facilitate peripheral nerve regeneration following injury.{53683} Cayman’s CGRP Monoclonal Antibody (Clone 4901) can be used for ICC applications.
    
                        
    
                                                                                                
    
                            
    宿主来源:
    
                            
    Mouse
    
                        
    
                                                                        
    
                            
    实验应用:
    
                            
    ICC
    
                        
    
                                                                                                
    
                            
    同种型:
    
                            
    IgG2a
    
                        
    
                                                                                                
    
                            
    免疫原:
    
                            
    Rat α-CGRP
    
                        
    
                                                                                                                        
    
                            
    克隆号:
    
                            
    4901
    
                        
    
                                                                                                                                                                                                
    
                            
    保存温度:
    
                            
    -20
    
                        
    
                                                                        
    
                            
    运输温度:
    
                            
    -20
    
                        
    
                                                                                                                        
    
                            
    产品形式:
    
                            
    100 µl of protein G-purified mouse monoclonal antibody
    
                        
    
                                                                                                
    
                            
    有效期:
    
                            
    365
    
                        
    
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                            
    
                                        
                                        
                                    
    
                
            
    
        
    
    
    
    
    
    
    
        
    
            
    
            
    
                
    
                    
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