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折扣/货期| 货号：11548 | 规格：100 µg | 目录价：￥4858 |
产品详情
产品名称:
BRDT bromodomain 1 (human, recombinant)
别名:
BRD6|Bromodomain testis-specific protein|Cancer/testis antigen 9|CT9|RING3-like protein
产品描述:
Key Features Cayman’s BRDT bromodomain 1 TR-FRET Assay Kit (Item No. 600650) was developed using BRDT bromodomain 1 (human, recombinant) protein.Bulk sizes available upon request The acetylation of histone lysine residues plays a crucial role in the epigenetic regulation of gene transcription. Acetylated lysine residues are recognized by a small protein domain known as a bromodomain.{19952} These domains function in the linking of protein complexes to acetylated nucleosomes, thereby controlling chromatin structure and gene expression. Thus, bromodomains serve as “readers” of histone acetylation marks regulating the transcription of target promoters.{20313} The BET family of proteins, defined by tandem Bromodomains and an Extra Terminal domain, include BRD2, BRD3, BRD4, and BRDT.{19953} The BET proteins play a key role in many cellular processes, including inflammatory gene expression, mitosis, and viral/host interactions.{19559,19558,19930} BRDT is similar to the RING3 protein family and possesses 2 bromodomain motifs and a PEST sequence motif, which is a region rich in proline (P), glutamic acid (E), serine (S), and threonine (T) residues known to have a short intracellular half-life. This product contains the bromodomain 1 region of BRDT.
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris, pH 7.5, containing 500 mM sodium chloride, 5% glycerol, and 5 mM β-mercaptoethanol
有效期:
730
纯度:
≥80% estimated by SDS-PAGE
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