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    Arachidonoyl amide
    品牌：Cayman
    货号：10007295-10 mg 规格：10 mg 目录价：￥1092
    货号：10007295-25 mg 规格：25 mg 目录价：￥2562
    货号：10007295-5 mg 规格：5 mg 目录价：￥574
    货号：10007295-50 mg 规格：50 mg 目录价：￥4508
    产品详情
    产品名称:
    Arachidonoyl amide
    别名:
    Arachidonamide|Arachidonic Acid amide
    产品描述:
    Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Anandamide (AEA) is an endogenous cannabinoid that binds to both central cannabinoid (CB1) and peripheral cannabinoid (CB2) receptors. The biological actions of AEA are terminated by cellular uptake and hydrolysis of the amide bond by the enzyme fatty acid amide hydrolase (FAAH). Arachidonoyl amide is an analog of anandamide (AEA) that lacks the hydroxyethyl moiety. It is hydrolyzed by FAAH more effectively than AEA but exhibits significantly weaker binding to the human CB1 receptor with a Ki of 9.6 µM.{2713,13257} Arachidonoyl amide and AEA exhibit similar binding and translocations into cells via the AEA transporter. It inhibits [3H]-AEA uptake into human astrocytoma cells with an IC50 of 9 µM.{13757} Arachidonoyl amide also inhibits rat glial gap junction cell-cell communication by 90% at a concentration of 20 µM.{8122}
    保存温度:
    -20
    运输温度:
    -20
    预期分子量:
    303.5
    产品形式:
    A solution in methyl acetate
    有效期:
    730
    纯度:
    ≥98%
    CAS号:
    85146-53-8
    分子式:
    C20H33NO
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