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Amyloid Beta 1-42 Oligomer Antibody: FITC
品牌：Stressmarq
货号：SMC-620D-FITC 规格：100 µg 目录价：￥7119
产品详情
产品名称:
Amyloid Beta 1-42 Oligomer Antibody: FITC
别名:
Abeta Oligomers Antibody, APP Antibody
产品描述:
Rabbit Anti-Human Amyloid Beta 1-42 Oligomer Recombinant Monoclonal IgG
反应种属:
Human
宿主来源:
Rabbit
实验应用:
WB | ELISA
靶标/特异性:
Amyloid Beta 1-42 oligomers
同种型:
IgG
免疫原:
Amyloid beta 1-42 oligomers (StressMarq Catalog# SPR-488)
免疫原种属:
Human
克隆性:
Recombinant Monoclonal
克隆号:
2F9
纯化方式:
Protein A Purified
偶联:
FITC
产品浓度:
0.5mg/ml
保存温度:
-20ºC
运输温度:
Blue Ice or 4ºC
存储溶液:
PBS pH 7.4, 50% glycerol, 0.09% sodium azide. *Storage buffer may change when conjugated
产地:
加拿大
功能与背景:
Our amyloid beta oligomer antibody (clone 2F9) has been tested for specificity against synthetic AB 1-42 aggregates, with higher specificity to oligomers demonstrated. In the brain, amyloid beta peptide (Aβ) is generated by protease cleavage of amyloid precursor protein (APP), which aggregates into oligomers, protofibrils, fibrils and ultimately plaques in neurodegenerative diseases. The accumulation of Aβ plaques in the brain is considered a hallmark of Alzheimer’s disease (AD), and most of the drugs tested for AD in the past 20 years have targeted amyloid beta accumulation (1). The immunogen used was our Amyloid Beta 1-42 (Aβ42) Oligomers are generated from Amyloid Beta Peptide 1-42 pre-treated with 1,1,1,3,3,3-Hexafluoro-2-propanol (HFIP) as previously published (2,3).
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