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折扣/货期| 货号：502100 | 规格：96 wells | 目录价：￥6412 |
产品详情
产品名称:
ACE2 Inhibitor Screening Assay Kit
别名:
ACEH|ACE-related Carboxypeptidase|Angiotensin-converting Enzyme 2|Angiotensin-converting Enzyme Homolog|Metalloprotease MPROT15
产品描述:
Cayman’s ACE2 Inhibitor Screening Assay Kit provides a robust and easy-to-use platform for testing potential inhibitors of human ACE2. The assay uses an ACE2-specific fluorogenic substrate, Mca-APK (Dnp). ACE2 cleaves this substrate generating free Mca, which can be easily quantified using a fluorescence plate reader at excitation and emission wavelengths of 320 and 405 nm, respectively. The potent and reversible ACE2 inhibitor MLN-4760 is included as a positive control. Human ACE2 plays an important role in regulating blood pressure. It is also known to bind SARS-CoV-2 spike. This assay can be used as a counter-screen for potential drug candidates to ensure they do not interfere with the normal physiological functions of ACE2.
保存温度:
-80
运输温度:
-80
有效期:
365
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