货号:CDX-M0156-G005 | 规格:5 g | 目录价:¥2310 |
产品详情
产品名称:
8-Methoxypsoralen
别名:
8-MP; 8-MOP; 8-Methoxy-6,7-furanocoumarin; 9-Methoxyfuro[3,2-g][1]benzopyran-7-one; 5-Demethoxyisoimpinellin; Ammoidin; Methoxsalen; Xanthotoxin
产品描述:
Methoxsalen (8-Methoxypsoralen) is a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). Has more potency than 5-MOP, 5-OH-P, DH-8-MOP and psoralen in inhibiting CYP2B1 (cytochrome P-450 2B1). Completely inhibits the metabolism of nicotine in vitro. Inhibits the metabolism of caffeine. Methoxsalen is a drug with photoactivating properties used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to UVA light. Upon photoactivation, ultraviolet A (UVA) irradiation induces monoadducts and interstrand cross-links in DNA and therefore can be used to study DNA repair and recombination mechanisms.
宿主来源:
Synthetic.
保存温度:
-20°C
运输温度:
Ambient
预期分子量:
216.19
产品形式:
solid
有效期:
Stable for at least 2 years after receipt when stored at -20°C.
产地:
瑞士
纯度:
>95% (HPLC)
CAS号:
298-81-7
分子式:
C12H8O4
溶解度:
Soluble in acetic acid or water (slightly).
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