货号:10006618 | 规格:1 ea | 目录价:¥1848 |
产品详情
产品名称:
5-OxoETE Receptor Blocking Peptide
别名:
R527|TG1019
产品描述:
To be used in conjunction with Cayman’s 5-OxoETE Receptor Polyclonal Antibody (Item No. 100025) to block protein-antibody complex formation during immunochemical analysis of 5-OxoETE. The 5-OxoETE receptor recognizes eicosatetraenoic acids and polyunsaturated fatty acids including 5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (5-OxoETE), which is the most potent ligand.{11953} 5-OxoETE is a potent stimulator of chemotaxis for eosinophils and neutrophils that mediates its action via a putative G-protein coupled receptor (GPCR).{10476,11003} The receptor couples to Gi/o to inhibit cyclic AMP production and to mobilize intracellular calcium.{10476,11003} Northern blot analysis reveals that the receptor is highly expressed on eosinophils and neutrophils, suggesting a key role in the inflammatory response.{11003} In addition, the protein can also be detected in tissues such as kidney and liver.{10476,11003}
保存温度:
-20
运输温度:
-20
产品形式:
200 µg of peptide
有效期:
1095
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