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17β-Estradiol
品牌:Cayman
货号:10006315-1 g 规格:1 g 目录价:¥434
货号:10006315-10 g 规格:10 g 目录价:¥2324
货号:10006315-500 mg 规格:500 mg 目录价:¥280
货号:10006315-5 g 规格:5 g 目录价:¥1456
产品详情
产品名称:
17β-Estradiol
别名:
17β-Oestradiol|E2|Estradiol|β-Estradiol
产品描述:
17β-Estradiol is the major pre-menopausal bioactive estrogen and an active metabolite of testosterone.{68406,68407,68408} It is produced primarily by the ovary, and to a lesser extent, by the adrenals, testes, and adipose tissue, as well as by the placenta during pregnancy.{68406} 17β-Estradiol binds to estrogen receptors localized to the nucleus, cytoplasm, and plasma membrane and induces gene transcription or non-genomic intracellular signaling in a locations-dependent manner.{68407} It regulates reproductive development in females and spermatogenesis in males, as well as various non-reproductive processes including lipid and glucose homeostasis, bone mass maintenance, cognition, energy balance, and dilation of blood vessels.{68407,68408} 17β-Estradiol deficiency due to hypogonadism or 17α-hydroxylase/17,20-lyase deficiency is associated with fatigue, incontinence, osteoporosis, depression, emotional instability, and hot flashes. Formulations containing 17β-estradiol have been used in the treatment of menopause symptoms and the prevention of osteoporosis.
保存温度:
-20
运输温度:
-20
预期分子量:
272.4
产品形式:
A crystalline solid
有效期:
1460
纯度:
≥98%
CAS号:
50-28-2
分子式:
C18H24O2
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