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VnP-16 (trifluoroacetate salt)
品牌:Cayman
货号:38839-1 mg 规格:1 mg 目录价:¥350
货号:38839-10 mg 规格:10 mg 目录价:¥2450
货号:38839-25 mg 规格:25 mg 目录价:¥5250
货号:38839-5 mg 规格:5 mg 目录价:¥1316
产品详情
产品名称:
VnP-16 (trifluoroacetate salt)
产品描述:
VnP-16 is a synthetic peptide fragment that corresponds to amino acids 270-281 of vitronectin, a multifunctional glycoprotein with roles in cell attachment, migration, and spreading.{51432} It induces attachment and cell spreading of isolated human osteogenic cells, an effect that can be reversed by siRNA knockdown of β1 integrin, when applied to cell plates at a concentration of 9.1 µg/cm2. VnP-16 induces osteogenesis of human skin-derived mesenchymal precursors and MC3T3-E1 mouse calvarial osteoblast precursors. In vivo, VnP-16 decreases IL-1α-induced bone loss and decreases the number of calvarial osteoclasts in mice. It also increases bone mineral density and decreases trabecular bone loss in a mouse model of ovariectomy-induced bone loss.
保存温度:
-20
运输温度:
-20
预期分子量:
1649.9
产品形式:
A solid
有效期:
1460
纯度:
≥98%
分子式:
C82H112N20O17 • XCF3COOH
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