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Thioredoxin Glutathione Reductase (Schistosoma mansoni, recombinant)
货号：39632 规格：250 µg 目录价：￥8932
产品详情
产品名称:
Thioredoxin Glutathione Reductase (Schistosoma mansoni, recombinant)
别名:
TGR
产品描述:
Thioredoxin glutathione reductase (TGR) is a selenocysteine-containing oxidoreductase flavoenzyme that protects Schistosoma, the genus of blood flukes that causes schistosomiasis, and other helminth parasites from host-induced oxidative damage.{72051,72052} It is a homodimer that contains an N-terminal glutathione reductase domain, an FAD- and NADPH- binding site, and a thioredoxin domain near the C-terminus, and it can reduce both DTNB and oxidized glutathione (GSSH).{72052} TGR catalyzes NADPH- and FAD-dependent reduction of oxidized thioredoxin (Trx), glutathione (GSH), and glutaredoxin (Grx), which mitigate the effects of reactive oxygen and nitrogen species released by host neutrophils and macrophages that can damage intracellular proteins and lipids.{72053} Cayman's TGR (Schistosoma mansoni, recombinant) protein can be used for enzyme activity assays.
保存温度:
-20
运输温度:
-20
产品形式:
TE buffer with 50% glycerol
有效期:
365
纯度:
≥95% estimated by SDS-PAGE
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