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TFE3 antibody, N-term
品牌:GeneTex
货号:GTX89882 规格:100μg 目录价:¥5600
产品详情
产品名称:
TFE3 antibody, N-term
别名:
transcription factor binding to IGHM enhancer 3 , RCCP2 , RCCX1 , TFEA , bHLHe33
反应种属:
Human
宿主来源:
Goat
实验应用:
WB
同种型:
IgG
免疫原:
Peptide with sequence SHAAEPARDGVEAS-C, from the N Terminus of the protein sequence according to NP_006512.2.
克隆性:
Polyclonal
克隆号:
纯化方式:
Purified by ammonium sulphate precipitation followed by antigen affinity chromatography
偶联:
Unconjugated
产品浓度:
0.50 mg/ml (Please refer to the vial label for the specific concentration.)
阳性对照:
The peptide used to generate this antibody is available for purchase (GTX89882-PEP).
保存温度:
Store as concentrated solution. Centrifuge briefly prior to opening vial. For short-term storage (1-2 weeks), store at 4ºC. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
运输温度:
4°C
预期分子量:
62
产品形式:
Liquid
存储溶液:
TBS, 0.5% BSA, 0.02% Sodium azide.
产地:
美国
功能与背景:
This gene encodes a basic helix-loop-helix domain-containing transcription factor that binds MUE3-type E-box sequences in the promoter of genes. The encoded protein promotes the expression of genes downstream of transforming growth factor beta (TGF-beta) signaling. This gene may be involved in chromosomal translocationss in renal cell carcinomas and other cancers, resulting in the production of fusion proteins. Translocations partners include PRCC (papillary renal cell carcinoma), NONO (non-POU domain containing, octamer-binding), and ASPSCR1 (alveolar soft part sarcoma chromosome region, candidate 1), among other genes. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]
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