Soluble Epoxide Hydrolase (human, recombinant)-其他酶-ELISA_抗体_蛋白_核苷酸

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Soluble Epoxide Hydrolase (human, recombinant)

品牌：Cayman

官网链接

说明书

折扣/货期

货号：10011669

规格：50 µg

目录价：￥5376

产品详情

产品名称:

Soluble Epoxide Hydrolase (human, recombinant)

别名:

Cytosolic Epoxide Hydrolase (CEH)|EPHX2|Epoxide Hydrolase 2|sEH

产品描述:

Soluble epoxide hydrolase (sEH) is a member of the α/β-hydrolase fold enzyme family that catalyzes the hydrolysis of bioactive fatty acid epoxides to inactive vicinal diols.{52737} It is a homodimer in which each subunit is composed of two domains, a C-terminal epoxide hydrolase domain and an N-terminal phosphatase domain.{52738,15765} sEH is localized to the cytoplasm or to peroxisomes in a tissue-specific manner and is found in various tissues, including skin, lung, uterus, kidney, brain, and myocardium.{52740,52739} sEH is also expressed in the vasculature and inhibition of sEH attenuates pathogenic vascular remodeling and hypertension via preservation of cardioprotective epoxyeicosatrienoic acids (EETs) in rat models of atherosclerosis and hypertension, respectively.{52741} Inhibition of sEH also has a protective role in various diseases, including inflammatory bowel disease, osteoarthritis, seizure, stroke, and Alzheimer’s disease, as well as in various chronic pain states.{52737,50771} Cayman’s Soluble Epoxide Hydrolase (human, recombinant) protein can be used for enzyme activity assays.

宿主来源:

Insect cells

保存温度:

-80

运输温度:

-80

产品形式:

TBS, pH 7.4, with 20% glycerol

有效期:

730

纯度:

≥95% estimated by SDS-PAGE