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折扣/货期| 货号：10316 | 规格：100 µg | 目录价：￥6720 |
产品详情
产品名称:
SIRT7 (human, recombinant)
别名:
NAD-dependent deacetylase 7|Silent Information Regulator 7|SIR2-like protein 7|SIR2L7|Sirtuin 7
产品描述:
The sirtuins represent a distinct class of trichostatin A-insensitive lysyl-deacetylases (class III HDACs) and have been shown to catalyze a reaction that couples lysine deacetylation to the formation of nicotinamide and O-acetyl-ADP-ribose from NAD+ and the abstracted acetyl group.{15271,15275,15273} There are seven human sirtuins, which have been designated SIRT1-SIRT7.{15274} SIRT7 has been shown to activate transcription by RNA polymerase I and deacetylate p53.{17220} SIRT7 prevents progressive functional deterioration of the heart, and is suggested to play an important role in regulation of stress responses and cell death in the heart.{17219}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM NaPO4, pH 7.2, with 100 mM NaCl and 20% glycerol
有效期:
365
纯度:
≥35% estimated by SDS-PAGE
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