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折扣/货期| 货号：F40198-0.08ML | 规格：0.08 ml | 目录价：￥2673.25 |
| 货号：F40198-0.4ML | 规格：0.4 ml | 目录价：￥5765.55 |
产品详情
产品名称:
SET07 Antibody
产品描述:
SET07 is a protein-lysine N-methyltransferase that monomethylates both histones and non-histone proteins. Specifically monomethylates 'Lys-20' of histone H4 (H4K20me1). H4K20me1 is enriched during mitosis and represents a specific tag for epigenetic transcriptional repression. Mainly functions in euchromatin regions, thereby playing a central role in the silencing of euchromatic genes. Required for cell proliferation, probably by contributing to the maintenance of proper higher-order structure of DNA during mitosis. Involved in chromosome condensation and proper cytokinesis. Nucleosomes are preferred as substrate compared to free histones. Mediates monomethylation of p53/TP53 at 'Lys-382', leading to repress p53/TP53-target genes. Plays a negative role in TGF-beta response regulation and a positive role in cell migration. [UniProt]
反应种属:
Human, Mouse
宿主来源:
Mouse
实验应用:
IHC, IF, WB, ELISA
同种型:
Mouse IgG1
免疫原:
This SET07 antibody was raised using purified recombinant GST fusion protein encoding the N-terminal region of human SET07.
克隆性:
Monoclonal (mouse origin)
纯化方式:
Purified
保存温度:
Aliquot the SET07 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.
存储溶液:
In 1X PBS pH 7.4 with 0.09% sodium azide
产地:
美国
生产商:
NSJ Bio
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