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SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged)
品牌：Cayman
货号：30429 规格：50 µg 目录价：￥15274
产品详情
产品名称:
SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged)
别名:
SARS-CoV-2 Surface Receptor Binding Domain|Severe Acute Respiratory Syndrome Coronavirus 2 Spike Glycoprotein Receptor Binding Domain
产品描述:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus, a member of the Betacoronavirus genus, and the causative agent of COVID-19.{53462,53459,53461,55257,55258} The SARS-CoV-2 spike glycoprotein, also known as the surface glycoprotein, is located on the outer envelope of the virion.{53462} It is composed of an S1 and S2 subunit divided by a furin S-cleavage site not found in other SARS-CoVs.{46767,49561} The S1 subunit contains the receptor-binding domain (RBD), which binds to the carboxypeptidase angiotensin-converting enzyme 2 (ACE2), and the S1 and S2 subunits are cleaved by the protease TMPRSS2 to facilitate viral fusion with the host cell membrane.{49542,49536,49558} In this way, ACE2 acts as the functional receptor for SARS-CoV-2. Cayman’s SARS-CoV-2 Spike Glycoprotein Receptor Binding Domain (human IgG1 Fc-tagged) protein can be used as an antigen or for Western blot, ELISA, protein-protein interaction studies, and other in vitro binding and in vivo functional assays.
宿主来源:
HEK293 cells
保存温度:
-80
运输温度:
-80
产品形式:
1 mg/ml in a solution of PBS, pH 7.2
有效期:
365
纯度:
≥90% estimated by SDS-PAGE
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