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SARS-CoV-2 nsp7 (recombinant)
货号：40881-100 µg 规格：100 µg 目录价：￥7644
货号：40881-500 µg 规格：500 µg 目录价：￥24780
产品详情
产品名称:
SARS-CoV-2 nsp7 (recombinant)
别名:
SARS-CoV-2 Non-structural Protein 7|Severe Acute Respiratory Syndrome Coronavirus 2 nsp7
产品描述:
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an enveloped positive-stranded RNA virus and the causative agent of COVID-19, a primarily respiratory illness characterized by fever, cough, and shortness of breath that can lead to life-threatening complications.{53462,53459,53461,55257,55258} The SARS-CoV-2 genome contains approximately 30 kilobases and 14 open reading frames (ORFs) that encode four structural proteins: spike, envelope, membrane, and nucleocapsid, as well as 16 non-structural proteins and 9 accessory factors.{57176} SARS-CoV-2 non-structural protein 7 (nsp7) is encoded within ORF1ab and is a cofactor in the RNA replication transcriptional complex. nsp7 is highly conserved in coronaviruses, and in SARS-CoV-2 it forms a decameric RNA replication transcriptional complex with the RNA polymerase cofactor nsp8 and the RNA-dependent RNA polymerase (RdRp) nsp12.{72344} Mutations in the nsp7-nps8 binding interface reduce the stability of the RNA replication transcriptional complex, leading to impaired RNA polymerase activity.{72345}
保存温度:
-80
运输温度:
-80
产品形式:
50 mM Tris-HCl, pH 7.5, with 200 mM sodium chloride and 20% glycerol
有效期:
365
纯度:
≥90%
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