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S7 (trifluoroacetate salt)

品牌：Cayman

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说明书

折扣/货期

货号：37467-1 mg	规格：1 mg	目录价：￥364
货号：37467-10 mg	规格：10 mg	目录价：￥2856
货号：37467-25 mg	规格：25 mg	目录价：￥6258
货号：37467-5 mg	规格：5 mg	目录价：￥1624

产品详情

产品名称:

S7 (trifluoroacetate salt)

别名:

Leu-Ser-Leu-Iso-Thr-Arg-Leu-OH

产品描述:

S7 is a peptide antagonist of the IL-6 receptor.{69504,69505} It inhibits IL-6 binding to the IL-6 receptor in a concentration-dependent manner.{69504} S7 (50 µM) inhibits IL-6-induced increases in VEGF levels in C-33 A cervical cancer cells and RPMI-8226 B cell lymphocytes. It reduces tumor volume in an IL-6-overexpressing C-33 A cervical cancer mouse xenograft model when administered at a dose of 50 mg/kg every two days. When coupled to cysteine and the surface of lipid nanoparticles (LNPs) encapsulating doxorubicin, S7 increases LNP glioma targeting and increases survival in a U251 glioblastoma mouse xenograft model. {69505}

保存温度:

-20

运输温度:

-20

预期分子量:

815

产品形式:

A solid

有效期:

1460

纯度:

≥95%