官网链接
折扣/货期| 货号：210-21-100ug | 规格：100ug | 目录价：￥22138 |
| 货号：210-21-10ug | 规格：10ug | 目录价：￥2836 |
| 货号：210-21-1mg | 规格：1mg | 目录价：￥88652 |
| 货号：210-21-250ug | 规格：250ug | 目录价：￥38710 |
| 货号：210-21-2ug | 规格：2ug | 目录价：￥1163 |
| 货号：210-21-500ug | 规格：500ug | 目录价：￥57513 |
| 货号：210-21-50ug | 规格：50ug | 目录价：￥13268 |
产品详情
产品名称:
Recombinant Murine IL-21
别名:
Interleukin-21, Za11
产品描述:
IL-21 is a pleiotropic cytokine produced by CD4+ T cells in response to antigenic stimulation. Its action generally enhances antigen-specific responses of immune cells. The biological effects of IL-21 include: inducing the differentiation of T cell-stimulated B cells into plasma cells and memory B cells; the stimulation of IgG production in conjunction with IL-4; and the induction of apoptotic effects in naive B cells and stimulated B cells in the absence of T cell signaling. Additionally, IL-21 promotes the anti-tumor activity of CD8+ T cells and NK cells. IL-21 exerts its effect through binding to a specific type I cytokine receptor, IL-21R, which also contains the gamma chain (gammac) found in other cytokine receptors, including IL-2, IL-4, IL-7, IL-9 and IL-15. The IL-21/IL-21R interaction triggers a cascade of events, which includes activation of the tyrosine kinases JAK1 and JAK3, followed by activation of the transcription factors STAT1 and STAT3. Recombinant Murine IL-21 is a 15.0 kDa protein consisting of 130 amino acid residues.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
15 kDa
产品形式:
Bulk
产地:
美国
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