货号:315-24-100ug | 规格:100ug | 目录价:¥5790 |
货号:315-24-10ug | 规格:10ug | 目录价:¥1169 |
货号:315-24-1mg | 规格:1mg | 目录价:¥25699 |
货号:315-24-250ug | 规格:250ug | 目录价:¥11215 |
货号:315-24-500ug | 规格:500ug | 目录价:¥16664 |
货号:315-24-50ug | 规格:50ug | 目录价:¥2910 |
产品详情
产品名称:
Recombinant Murine GDF-5 (BMP-14/CDMP-1)
别名:
Growth/Differentiation Factor-5, BMP-14, Cartilage-Derived Morphogenetic Protein-1 (CDMP-1)
产品描述:
GDF-5 is expressed in long bones during embryonic development and postnatally in articular cartilage. Mutations in the GDF-5 gene have been implicated in Hunter-Thompson type dwarfism and in Grebe Syndrome, which is characterized by short stature, extra digits, and short and deformed extremities. The mature and functional form of GDF-5 is a homodimer of two 120 amino acid polypeptide chains (monomers) linked by a single disulfide bond. Each GDF-5 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 27 amino acid signal peptide and a 348 amino acid propeptide. This precursor undergoes intracellular dimerization, and upon secretion it is processed by a furin-type protease. Recombinant Murine GDF-5 is a 27.0 kDa homodimeric disulfide-linked protein consisting of two 120 amino acid polypeptide chains.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
27 kDa
产品形式:
Bulk
产地:
美国
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