Recombinant Human Wnt-7a-细胞因子、趋化因子与生长因子-ELISA_抗体_蛋白_核苷酸

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Recombinant Human Wnt-7a

品牌：PeproTech

官网链接

说明书

折扣/货期

货号：120-31-100ug	规格：100ug	目录价：￥20419
货号：120-31-15ug	规格：15ug	目录价：￥2836
货号：120-31-1mg	规格：1mg	目录价：￥81826
货号：120-31-3ug	规格：3ug	目录价：￥1163
货号：120-31-500ug	规格：500ug	目录价：￥53083

产品详情

产品名称:

Recombinant Human Wnt-7a

别名:

None.

产品描述:

Wnt-7a belongs to the Wnt family of signaling proteins that play a key role in maintaining the integrity of embryonic and adult tissues. It is expressed in placenta, kidney, testis, uterus, fetal lung, and fetal and adult brain. Most Wnt proteins can signal though a mechanism called the canonical Wnt pathway, in which Wnt proteins bind to and activate seven-pass transmembrane receptors of the Frizzled family, ultimately leading to the disruption of beta-catenin degradation. Intracellular accumulation of beta-catenin increases translocations of the protein into the nucleus, where it binds to TCF/LEF transcription factors to induce the expression of numerous genes. Increased Wnt/beta-catenin signaling is associated with tumorigenesis in a diverse set of human cancers. However, Wnt-7a/Frizzled-9 signaling has been shown to act as a tumor suppressor in non-small cell lung cancers. Recombinant Human Wnt-7a is a 35.5 kDa glycoprotein containing 318 amino acids. Due to glycosylation, Wnt-7a migrates between 40-55 kDa by SDS-PAGE gel under unreduced conditions.

宿主来源:

HEK293 cells

推荐稀释度:

请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度

预期分子量:

35.5 kDa

产品形式:

Bulk

产地:

美国

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