货号:300-01A-100ug | 规格:100ug | 目录价:¥5760 |
货号:300-01A-10ug | 规格:10ug | 目录价:¥1163 |
货号:300-01A-1mg | 规格:1mg | 目录价:¥25574 |
货号:300-01A-250ug | 规格:250ug | 目录价:¥11161 |
货号:300-01A-500ug | 规格:500ug | 目录价:¥16583 |
货号:300-01A-50ug | 规格:50ug | 目录价:¥2900 |
产品详情
产品名称:
Recombinant Human TNF-alpha
别名:
Tumor Necrosis Factor, TNFSF2, Cachectin, Differentiation-inducing factor (DIF), Necrosin, Cytotoxin
产品描述:
TNF-alpha is a pleiotropic pro-inflammatory cytokine secreted by various cells, including adipocytes, activated monocytes, macrophages, B cells, T cells and fibroblasts. It belongs to the TNF family of ligands, and signals through two receptors, TNFR1 and TNFR2. TNF-alpha is cytotoxic to a wide variety of tumor cells, and is an essential factor in mediating the immune response against bacterial infections. TNF-alpha also plays a role in the induction of septic shock, autoimmune diseases, rheumatoid arthritis, inflammation, and diabetes. Human and murine TNF-alpha demonstrate significant cross-species reactivity. TNF-alpha exists in two forms; a type II transmembrane protein, and a mature soluble protein. The TNF-alpha transmembrane protein is proteolitically cleaved to yield a soluble, biologically active, 17 kDa TNF-alpha, which forms a non-covalently linked homotrimer in solution. Recombinant Human TNF-alpha is a soluble 157 amino acid protein (17.4 kDa) which corresponds to C-terminal extracellular domain of the full length transmembrane protein.
宿主来源:
E.coli
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
17.4 kDa
产品形式:
Bulk
产地:
美国
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