货号:160-01-100ug | 规格:100ug | 目录价:¥11600 |
货号:160-01-1mg | 规格:1mg | 目录价:¥51397 |
货号:160-01-200ug | 规格:200ug | 目录价:¥19234 |
货号:160-01-25ug | 规格:25ug | 目录价:¥2910 |
货号:160-01-500ug | 规格:500ug | 目录价:¥33338 |
货号:160-01-5ug | 规格:5ug | 目录价:¥1169 |
产品详情
产品名称:
Recombinant Human TLR-3
别名:
Toll-like receptor 3, CD283 antigen
产品描述:
TLR-3 is a single-pass type I receptor that binds to and signals the presence of microbial pathogens and double stranded RNA (dsRNA) viruses. Signaling through TLR-3 can promote the NF-kappaB pathway to initiate innate and adaptive immune responses to bacterial and viral infections, as well as the p53 pathway to trigger apoptosis in cells infected with dsRNA viruses. TLR-3 belongs to a family of structurally-related toll-like receptors (TLRs) containing an N-terminal domain rich in leucine repeats, and a C-terminal intracellular Toll/interleukin (IL)-1 (TIL) domain. TLR-3 is expressed primarily in dendritic cells of the placenta and pancreas where it can reside on both sides of the plasma membrane, and in the endosomal compartment of the cells. Recombinant Human TLR-3 is 77.4 kDa glycoprotein containing 681 residues which comprise the TLR-3 extracellular domain.
宿主来源:
HEK293 cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
77.4 kDa
产品形式:
Bulk
产地:
美国
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