• 九游会j9网站首页,j9九游会首页登录,j9九游会ag真人官网

    深圳九游会j9网站首页有限公司 a1

    Recombinant Human Thrombomodulin
    品牌:PeproTech
    货号:100-58-100ug 规格:100ug 目录价:¥16593
    货号:100-58-10ug 规格:10ug 目录价:¥2836
    货号:100-58-1mg 规格:1mg 目录价:¥66482
    货号:100-58-250ug 规格:250ug 目录价:¥29043
    货号:100-58-2ug 规格:2ug 目录价:¥1163
    货号:100-58-500ug 规格:500ug 目录价:¥43140
    产品详情
    产品名称:
    Recombinant Human Thrombomodulin
    别名:
    CD141, BDCA-3, THBD, TM
    产品描述:
    Thrombomodulin (TM, CD141, THBD) is an endothelial cell-expressed, transmembrane glycoprotein that can form a complex with the coagulation factor, thrombin. The thrombomodulin/thrombin complex converts protein C to its activated form, protein Ca, which in turn proteolytically cleaves and deactivates factor Va and factor VIIIa, two essential components of the coagulation mechanism. This inactivation reduces the generation of additional thrombin, and thereby effectively prevents continued coagulation. Reduced levels of thrombomodulin can correlate with the pathogenesis of certain cardiovascular diseases, such as atherosclerosis and thrombosis. However, the serum levels of the truncated circulating form of thrombomodulin are typically elevated during inflammation and in the presence of various inflammatory-related diseases. The thrombomodulin protein contains 575 amino acids, including an 18 a.a. signal sequence, a 497 a.a. extracellular domain, a 24 a.a. transmembrane sequence, and a 36 a.a. cytoplasmic region. Recombinant Human Thrombomodulin is a 51.4 kDa, 491-amino-acid length glycoprotein containing the extracellular domain of thrombomodulin.
    宿主来源:
    HEK293 cells
    推荐稀释度:
    请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
    预期分子量:
    51.4 kDa
    产品形式:
    Bulk
    产地:
    美国
    在线留言
    咨询类型
    联系人
    *
    联系方式
    *
    单位名称
    *
    咨询内容
    *
    九游会j9网站首页