官网链接
折扣/货期| 货号：200-06RC-100ug | 规格：100ug | 目录价：￥12757 |
| 货号：200-06RC-1mg | 规格：1mg | 目录价：￥51148 |
| 货号：200-06RC-20ug | 规格：20ug | 目录价：￥2836 |
| 货号：200-06RC-250ug | 规格：250ug | 目录价：￥22322 |
| 货号：200-06RC-500ug | 规格：500ug | 目录价：￥33176 |
| 货号：200-06RC-50ug | 规格：50ug | 目录价：￥7662 |
| 货号：200-06RC-5ug | 规格：5ug | 目录价：￥1163 |
产品详情
产品名称:
Recombinant Human sIL-6 Receptor alpha (CHO derived)
别名:
soluble IL-6 receptor alpha, B cell stimulatory factor-2, CD126
产品描述:
IL-6 mediates its biological effects through the type I IL-6 receptor system that consists of two chains, IL-6Ralpha and gp130. While the IL-6Ralpha chain is the binding component specific to IL-6, the gp130 chain only transmits signals of IL-6 when bound to IL-6Ralpha. The gp130 can also transmit signals from LIF, OSM, CNTF, IL-11 and CT-1 in conjunction with other receptor subunits. The low-affinity binding site for IL-6 is composed of IL-6Ralpha alone. IL-6Ralpha is expressed in a wide range of cells, including T cells, fibroblasts and macrophages. Soluble IL-6Ralpha, which consists of only the extracellular domain of the IL-6Ralpha chain, acts as an agonist of IL-6 activity at low concentrations. PeproTech's CHO cell-derived Recombinant Human sIL-6 Receptor alpha is a 37.9 kDa glycoprotein corresponding to 339 amino acid residues of the extracellular domain of IL-6Ralpha. As a result of glycosylation, Recombinant Human sIL-6 Receptor alpha migrates with an apparent molecular mass of approximately 57-70 kDa by SDS-PAGE gel, under reducing conditions.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
37.9 kDa
产品形式:
Bulk
产地:
美国
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