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折扣/货期| 货号：310-03H-100ug | 规格：100ug | 目录价：￥18291 |
| 货号：310-03H-10ug | 规格：10ug | 目录价：￥2836 |
| 货号：310-03H-1mg | 规格：1mg | 目录价：￥73308 |
| 货号：310-03H-250ug | 规格：250ug | 目录价：￥32010 |
| 货号：310-03H-2ug | 规格：2ug | 目录价：￥1163 |
| 货号：310-03H-500ug | 规格：500ug | 目录价：￥47559 |
产品详情
产品名称:
Recombinant Human sFas Ligand
别名:
soluble Fas Ligand (sFasL), TNFSF6, CD95L, Apo I Ligand, APTL
产品描述:
Fas Ligand (FasL) is a member of the TNF superfamily that is expressed on the cell surface of activated T cells. Binding of FasL to Fas Receptor triggers apoptosis in Fas-bearing cells. FasL has the ability to kill T cells and activated B cells, which leads to down-regulation of the immune response. The mechanism of Fas-induced apoptosis involves recruitment of pro-caspase 8 through an adaptor molecule called FADD, followed by processing of the pro-enzyme into active forms. These active caspases then cleave various cellular substrates, leading to the eventual cell death. Both human and murine sFasL are fully active on human and murine cells. Recombinant Human soluble Fas Ligand is a 17.9 kDa protein comprising the TNF-homologous region of FasL and contains an 8-residue N-terminal His-Tag.
宿主来源:
CHO cells
推荐稀释度:
请严格按照批次特异性说明书中Reconstitution部分指定的溶液溶解蛋白到推荐浓度
预期分子量:
17.9 kDa
产品形式:
Bulk
产地:
美国
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